HYPOPHOSPHATASIA (HPP) IN ADULTS

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How do I know if my symptoms are HPP?”

Everyone’s journey to discovering HPP is different. With many different symptoms, including chronic pain or premature tooth loss, it’s often hard to land
on a correct diagnosis. But if you still feel like something’s not right, take the
next step and talk to your doctor.

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CAROL, LIVING WITH HPP,
AND HER HUSBAND, BILL

The hallmark of HPP can be found with a simple blood test.

Throughout your journey, you may have experienced several kinds of tests. But when it comes to how HPP is diagnosed, have your doctor check for low alkaline phosphatase (ALP), because…

Low ALP

PERSISTENTLY
LOW
AGE- AND
SEX-ADJUSTED ALP

+
HPP Symptoms

ONE OR MORE HPP SYMPTOMS

=
Diagnose

MAY BE ENOUGH FOR
YOUR DOCTOR TO
DIAGNOSE HPP

If you or your doctor suspects HPP based on your symptoms and history,
a blood test to check your ALP levels can confirm the diagnosis.* Check with your doctor for more information; only a licensed healthcare professional can diagnose HPP.

*After your doctor has ruled out other causes of low ALP

MORE ON ALP

HPP can be misdiagnosed.

If you’ve been diagnosed with, or suspected to have had, conditions like rickets, rheumatoid arthritis, or another misdiagnosis with bone or muscle pain, you may want to have your doctor
re-review your medical history.

SOME COMMON MISDIAGNOSES OF HPP ARE:

OSTEOPOROSIS/
OSTEOPENIA

A condition that weakens bones and creates a greater risk of unexpected bone fractures.

RICKETS/
OSTEOMALACIA

A condition that causes bone pain and soft, weak bones.

FIBROMYALGIA

A condition that causes fatigue, brain fog, and musculoskeletal pain.

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