Complicated disease.

Simple diagnosis.

Hypophosphatasia (HPP) can cause many signs and symptoms. One test for low alkaline phosphatase (ALP) can lead to a diagnosis.

The first step to diagnosing HPP is noticing the visible signs and symptoms of the disease. You can help your doctor get to a diagnosis by sharing all the symptoms you have experienced.

If you are seeing a new doctor for the first time, make sure you have your medical records sent over before your appointment. You can ask your previous doctor to send them or you can ask to have a copy of them to keep in your own files and share with future doctors.

How your doctor will diagnose HPP

If you are experiencing signs and symptoms of HPP, here are a few steps you can take to help get the right diagnosis.

Make an appointment with your doctor.
Ask your doctor about measuring your ALP activity with one simple blood test.
Discuss your test results with your doctor. If your ALP is low for someone of your age and gender, your doctor may diagnose you with HPP.

All about ALP

ALP—an enzyme that is key for building healthy bones—is low in people with HPP.

Your doctor can identify low ALP with a simple blood test.

In healthy people and people with HPP, ALP levels vary throughout life—normal ALP levels are higher in infants, children, and adolescents than they are in adults—so when your test results become available, your doctor should check to see if your ALP is low for someone of your age and gender.

Download the ALP test results form and bring it to your doctor on the day of your ALP test.