Premature Tooth Loss: A Dental Symptom of Hypophosphatasia

Dental

In hypophosphatasia (HPP), premature tooth loss is a common presenting symptom.^1-7

Photograph showing an incisor with an intact root from a patient with hypophosphatasia versus an incisor with the root absorbed from a healthy patient

Image courtesy of Research Center, Shriners Hospitals for Children—St. Louis

Left: Incisor with root intact from patient with hypophosphatasia. Right: Incisor with root absorbed.

In hypophosphatasia, defective acellular root cementum results in compromised peridontal attachment.^1,8,9 Patients may experience^2-9:

Premature tooth loss—with the root intact—before the age of five

Nontraumatic tooth loss at any age

Dentists play a critical role in identifying hypophosphatasia.

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Dental

In hypophosphatasia (HPP), premature tooth loss is a common presenting symptom.^1-7

In hypophosphatasia, defective acellular root cementum results in compromised peridontal attachment.^1,8,9 Patients may experience^2-9:

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information about Hypophosphatasia.

Choose an icon to learn more

Dental

In hypophosphatasia (HPP), premature tooth loss is a common presenting symptom.1-7

In hypophosphatasia, defective acellular root cementum results in compromised peridontal attachment.1,8,9 Patients may experience2-9:

Keep Me UpdatedI want to know the latest news and information about Hypophosphatasia.

In hypophosphatasia (HPP), premature tooth loss is a common presenting symptom.^1-7

In hypophosphatasia, defective acellular root cementum results in compromised peridontal attachment.^1,8,9 Patients may experience^2-9:

Keep Me Updated
I want to know the latest news and
information about Hypophosphatasia.