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Low alkaline phosphatase: The biological hallmark of hypophosphatasia
Life-threatening.
Progressive.
Systemic.
Inherited.1,2
Low alkaline phosphatase (ALP) is the biological hallmark of hypophosphatasia (HPP) 1,3,4
Patients of all ages have a high burden of disease.1
How might patients in your practice be impacted by hypophosphatasia? Choose a patient type to learn more.
Follow the progressive course of HPP.
Devastating consequences. Lifelong Impact.
As a result of low alkaline phosphatase activity and defective bone mineralization, patients may experience any number of these unpredictable and devastating symptoms throughout life.1,3,5,6
Choose an icon to learn more
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Dental
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Skeletal
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Muscular/Rheumatologic
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Respiratory
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Neurologic
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Renal
Accurately diagnose hypophosphatasia
Misdiagnosis occurs often because the clinical presentation of hypophosphatasia can overlap with those of other metabolic disorders1,12,20,23
How do you
identify hypophosphatasia
in your practice?
Learn about critical care indicators, hallmarks, and early-onset symptoms
Low alkaline phosphatase is the biological hallmark of hypophosphatasia.1,4
Growth and development profoundly affect the normal interval for alkaline phosphatase.25,26
Assess your patient’s alkaline phosphatasePatient and family experiences with hypophosphatasia
- Brittan and her mother share Brittan’s lifelong struggles with hypophosphatasia.
- Dawn discusses the importance of getting the right diagnosis.
- Julie discusses the challenges of growing up with hypophosphatasia.
- Sueann talks about what it was like to get diagnosed with hypophosphatasia and her concerns about how it might affect her children.
- The Browns recall their difficulties finding the right diagnosis and treatment advice for their child with hypophosphatasia.
- Aubrey’s mother, Amy, talks about raising and caring for a child with hypophosphatasia.
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