What are some common misdiagnoses and diseases that can look like hypophosphatasia (HPP)?

Several conditions share symptoms with HPP, leading to common misdiagnoses from healthcare providers (HCPs). HCPs may initially look for common diseases over rare ones, or for conditions within their specialty.

These are some diagnoses people with HPP may receive before getting their correct HPP diagnosis:

Bones: Nutritional rickets, X-linked hypophosphatemic rickets, osteopenia/
osteoporosis, osteogenesis imperfecta, osteomalacia

Joints: Osteoarthritis/arthritis, rheumatoid arthritis, fibromyalgia, pseudogout (gout without urate crystal formation)

Teeth: Gum disease, dentinogenesis imperfecta