What are some common misdiagnoses and diseases that can look like hypophosphatasia (HPP)?

Several conditions share symptoms with HPP, leading to common misdiagnoses from healthcare providers (HCPs).HCPs tend to look first for common diseases over rare ones, or for conditions within their specialty

These are some diagnoses people with HPP may receive before getting their correct HPP diagnosis.

Bones: Nutritional rickets, X-linked hypophosphatemic rickets, osteopenia/osteoporosis, osteogenesis imperfecta, osteomalacia

Joints: Osteoarthritis/arthritis, rheumatoid arthritis, fibromyalgia, pseudogout (gout without urea crystal formation)

Teeth: Gum disease, dentinogenesis imperfecta