What’s the significance of persistently low alkaline phosphatase (ALP)?

ALP is an enzyme in the body that is crucial for the development of strong, healthy bones. When a person has persistently low ALP, this can contribute to many of the symptoms people with hypophosphatasia (HPP) experience, including frequent bone injuries and premature tooth loss.

It is important for your healthcare provider to observe ALP levels over time, as persistently low ALP may be a sign of HPP.